In the clinic, a single subcutaneous LEN injection (20 mg to 750 mg) in people with HIV (PWH) induced a strong antiviral response, with a >2.3 mean log10 decrease in HIV-1 RNA at day 10. Vaccines for COVID19: A Critical Appraisal with Dr. Carol Baker. 4.621 Impact Factor. shows a rising trend. View aims and scope Submit your article Guide for authors. Dedicated to saving lives through appropriate use and development of antibiotics now and in the future. Here, we investigated trends of susceptibilities to zoliflodacin in 986 isolates collected from men between 2014 and 2018.... Trichosporon asahii is an opportunistic fungal pathogen that can cause severe infections with high mortality rates. Human cytomegalovirus (HCMV) is a ubiquitous pathogen that can cause developmental disorders following congenital infection and life-threatening complications among transplant patients. Menu. Journal Citation Reports (Clarivate Analytics, 2020) 5-Year Impact Factor: 2.577 ℹ Five-Year Impact Factor: 2019: 2.577 Fluconazole has been associated with higher mortality compared with the echinocandins in patients treated for invasive candida infections. This multicenter study examined the PK and probability of pharmacokinetic-pharmacodynamic (PK-PD) target attainment... Chagas disease reactivation in HIV-positive people is an opportunistic infection with 79 to 100% mortality. Infection and Immunity. It is published by American Society for Microbiology. Current treatment options are scarce, particularly against carbapenem-resistant Acinetobacter baumannii (CRAB). Citescore is produced by Scopus, and can be a little higher or different compared to the impact factor produced by Journal Citation Report. Articles & Issues. Antimicrobial Agents and Chemotherapy is a major forum exclusively devoted to antimicrobial, antiviral, antiparasitic, and anticancer agents and chemotherapy. ASM journals are the most prominent publications in the field, delivering up-to-date and authoritative coverage of both basic and clinical microbiology. Many scientists attempt to publish their work in a journal with the highest possible journal impact factor (IF). Antimicrobial Agents Chemotherapy 2017 Feb 23; 61(3). is 4.68, which is computed in 2019 as per it's definition. The fungistatic activity of all-trans retinoic acid (ATRA) has been recently described in vitro. 6.7 CiteScore. Physiological changes in critically ill patients may affect the exposure of fluconazole, and therefore dosing adjustments might be needed. Journal description. ANTIMICROBIAL AGENTS Official journal of the International Society of Antimicrobial Chemotherapy AUTHOR INFORMATION PACK TABLE OF CONTENTS. The phosphodiesterase inhibitor tetrahydrophthalazinone NPD-008 was explored by phenotypic in vitro screening, target validation, and ultrastructural approaches against Trypanosoma cruzi.
Published monthly, the Journal features original articles on the laboratory aspects and clinical use of … Source: https://www.scimagojr.com/journalrank.php, IEEE Article Visit the official website of the journal/conference for the call for paper, submission guidelines, notification date, and submission deadlines. Editor-in-Chief: J.M. We evaluated β-lactam-resistant baseline Enterobacterales species and Pseudomonas aeruginosa lower respiratory tract isolates collected during the ASPECT-NP phase 3 clinical trial evaluating the safety and efficacy of ceftolozane-tazobactam compared with meropenem for the treatment of nosocomial pneumonia in ventilated adults. Purchase International Journal of Antimicrobial Agents. XXX. The foremost regulator of the oxidative stress response has been found to be OxyR. Although the clinical applicability of vancomycin for infants has been increasing, the pharmacokinetic data for vancomycin in extremely low-birth-weight infants are limited. Impact Factor: 4.615 Ahmed A, Schriever C, Britt N , Yager J, Amin R, McGuey L, Patel N. Comparing drug interaction frequencies of various hepatitis C treatment regimens among monoinfected patients. The Journal publishes primarily in human medicine, and articles in veterinary medicine likely to have an impact on global health. Memprediksi dampak dan kinerja jurnal masa depan melalui kebijaksanaan orang banyak. Attractive targets for chemotherapeutic intervention are the cytochrome (cyt) bc1 complex, which is an essential component of the mitochondrial electron transport chain (... Mycobacterium abscessus exhibits arr (ADP-ribosyltransferase)-dependent rifampin resistance. Due to a lack of approved drugs to treat polyomavirus infections, cidofovir, a phosphonate nucleotide analog approved to treat cytomegalovirus infections, has been repurposed as an antipolyomavirus agent. Antifungal prophylaxis is recommended to prevent invasive fungal disease caused by Candida spp., Aspergillus spp., and Pneumocystis jirovecii in patients at risk for opportunistic infections, such as allogeneic blood or marrow transplant recipients, patients with hematological disease undergoing chemotherapy, or patients on immunosuppressive... Oxidizing agents like hypochlorous acid (HOCl) have antimicrobial activity. In Enterobacteriaceae, the PhoQ/PhoP and PmrB/PmrA two-component systems regulate many genes that confer resistance to both polymyxins and host antimicrobial peptides. We characterized a multidrug-resistant (MDR) Enterobacter spp. Lenacapavir (LEN; GS-6207) is a potent first-in-class inhibitor of HIV-1 capsid with long-acting properties and the potential for subcutaneous dosing every 3 months or longer. We present an in vitro susceptibility assay for Madurella mycetomatis hyphae using resazurin for endpoint reading. Molecular genotyping holds tremendous potential to detect antimalarial drug resistance (ADR) related to single nucleotide polymorphisms (SNPs). Antimicrobial Agents and Chemotherapy is a peer-reviewed scientific journal published by the American Society for Microbiology.It covers antimicrobial, antiviral, antifungal, and antiparasitic agents and chemotherapy.The editor-in-chief is Cesar A. Arias (University of Texas Health Science Center at Houston). The ISSN of Antimicrobial Agents and Chemotherapy journal is 10986596, 00664804. Ganciclovir is indicated for curative or preventive treatment of cytomegalovirus (CMV) infections. Gallium nitrate (GaNt), an FDA-approved medication for cancer-related hypercalcemia, recently showed good activity against several clinically significant bacteria. Type I Interferon Signaling Is a Common Factor Driving Streptococcus pneumoniae and Influenza A Virus Shedding and Transmission Respiratory tract infections are a leading cause of childhood mortality and, globally, Streptococcus pneumoniae is … Antimicrobial activity and additive effect of the modified Gingyo-san with antimicrobials against Helicobacter pylori. However, the pharmacokinetic-toxicodynamic (PK-TD) relationship remains unclear. Antimicrobial Agents and Chemotherapy is published by American Society for Microbiology. It was established in 1972 by Gladys Lounsbury Hobby. Hundreds of millions of people are targeted with mass drug administration (MDA) of donated benzimidazole anthelmintics. Recently, an antimalarial quinoxaline derivative (MMV007204) from the Medicines for Malaria Venture (MMV) Malaria Box demonstrated promise against Schistosoma mansoni. The Journal of Antimicrobial Chemotherapy is a journal of the British Society for Antimicrobial Chemotherapy (BSAC) and is among the foremost international journals in antimicrobial research. Using this assay, reproducible MICs were obtained for amphotericin B, itraconazole, voriconazole, posaconazole, terbinafine, and micafungin. 1 to 65; 1972 to 2021; Vol. Antimicrobial Agents and Chemotherapy (AAC)Based on interdisciplinary research, an understanding of the basic mechanisms and therapeutic applications of microbial and antiparasitic agents and chemotherapy is established. Relebactam/imipenem/cilastatin is approved in the United States to treat complicated urinary tract and intra-abdominal infections in patients who have limited or no alternative treatment options and hospital-acquired bacterial pneumonia (HABP)/ventilator-associated bacterial pneumonia (VABP). Underexposure from current fluconazole dosing regimens may contribute to these worse outcomes, so alternative dosing strategies require study. Download PDF. Beside resistance, intracellular survival is another reason for failure to eradicate bacteria with antibiotics. A minireview and a short article, published in Antimicrobial Agents and Chemotherapy, a journal of the American Society for Microbiology, suggest that therapeutic drugs targeting SARS-CoV-2 directly will be most effective. Anti-Cancer Agents in Medicinal Chemistry aims to cover all the latest and outstanding developments in medicinal chemistry and rational drug design for the discovery of anti-cancer agents.. Each issue contains a series of timely in-depth/mini reviews and guest edited issues written by leaders in the field covering a range of current topics in cancer medicinal chemistry. Antimicrobial Agents and Chemotherapy® (AAC) features interdisciplinary studies that build our understanding of the underlying mechanisms and therapeutic applications of antimicrobial and antiparasitic agents and chemotherapy. The Journal publishes articles that further knowledge and advance the science and application of antimicrobial chemotherapy with antibiotics and antifungal, antiviral and antiprotozoal agents. SJR acts as an alternative to the Journal Impact Factor (or an average number of citations received in last 2 years). There is an urgent need for novel agents to treat drug-resistant bacterial infections, such as multidrug-resistant Staphylococcus aureus (MRSA). isolate (Ec61) was recovered in 2014 from a transtracheal aspirate sample from a patient admitted to a Brazilian tertiary hospital and submitted to further microbiological and genomic characterization. This 5-year, prospective, observational study tracked susceptibility changes and clinical outcomes in CF patients in the United States with chronic P. aeruginosa infection. The overall rank of Antimicrobial Agents and Chemotherapy is 1266. Journal Impact 2018 di Antimicrobial Agents and Chemotherapy è 4.680 (Ultimi dati nel 2019). antimicrobial agents and chemotherapy New Perspectives on Antimicrobial Agents: Remdesivir Treatment for COVID-19 Remdesivir was recently approved by the Food and Drug Administration for the treatment of hospitalized patients with coronavirus disease 2019 (COVID-19). An International Standard Serial Number (ISSN) is a unique code of 8 digits. • Description • Audience • Impact Factor • Abstracting and Indexing • Editorial Board • Guide for Authors p.1 p.1 p.1 p.2 p.2 p.4 ISSN: 0924-8579 DESCRIPTION. View editorial board. It is used for the recognition of journals, newspapers, periodicals, and magazines in all kind of forms, be it print-media or electronic. Pharmacokinetics of drugs can be affected by physiologic changes during pregnancy. It means 232 articles of this journal have more than 232 number of citations. Toxoplasma gondii is a globally distributed apicomplexan parasite and the causative agent of toxoplasmosis in humans. The ISSN of Antimicrobial Agents and Chemotherapy is 10986596, 00664804. Active efflux confers intrinsic resistance to multiple antibiotics in Pseudomonas aeruginosa, including old disused molecules. The best quartile for this journal is Q1. The Journal Impact 2019-2020 of Antimicrobial Agents and Chemotherapy is 4.680, which is just updated in 2020. It is used for the recognition of journals, newspapers, periodicals, and magazines in all kind of forms, be it print-media or electronic. 4.621 Impact Factor. It commonly involves the central nervous system (CNS). The h-index is a way of measuring the productivity and citation impact of the publications. ... 2019/2020 Annual … Uncommon mechanisms of resistance escape detection by these platforms and undermine our ability to contain outbreaks. An ISSN is a unique code of 8 digits. Note: The impact factor shown here is equivalent to citescore and is, therefore, used as a replacement for the same. Nitrofurantoin (NIT) is a broad-spectrum bactericidal antibiotic used in the treatment of urinary tract infections. Despite its being approved nearly 50 years ago, published information on its pharmacokinetic (PK) profile is limited. Antimicrobial Agents and Chemotherapy. Our readership includes representatives of academia, industry and health services, and includes those who are influential in formulary decisions. The impact factor (IF), also denoted as Journal impact factor (JIF), of an academic journal is a measure of the yearly average number of citations to recent articles published in that journal. ACM American Society for Microbiology Praziquantel (PZQ) has been the primary treatment for schistosomiasis for nearly 4 decades. Antimicrobial Agents and Chemotherapy Impact Factor, IF, number of article, … As a follow-up to the previous “History of Antimicrobial Agents and Chemotherapy from 1972 to 1998” written by George A. Jacoby (Antimicrob Agents Chemother 43:999–1002, 1999,... A common strategy to identify new antiparasitic agents is the targeting of proteases, due to their essential contributions to parasite growth and development. Here, we report on the anti-influenza virus activity of the mannose-binding agents Hippeastrum hybrid agglutinin (HHA) and Galanthus nivalis agglutinin (GNA) and the (N-acetylglucosamine)n-specific Urtica dioica agglutinin (UDA). The impact factor (IF) 2018 of Antimicrobial Agents and Chemotherapy Within the circumscriptions set forth below, any report involving studies of or with antimicrobial, antiviral (in-cluding antiretroviral), antifungal, or antiparasitic agents as these relate to human disease is within the purview of AAC. Antimicrobial Agents and Chemotherapy® features interdisciplinary studies that build our understanding of the underlying mechanisms and therapeutic applications of antimicrobial and antiparasitic agents and chemotherapy. The British Society for Antimicrobial Chemotherapy is an inter-professional organisation with over 40 years of experience and achievement in antibiotic education, research and leadership. About the Journal . Compared with historical Journal Impact data, the Metric 2019 of Antimicrobial Agents and Chemotherapy grew by 3.54%. 1752 N St. NW Antimicrobial Agents and Chemotherapy has an h-index of 232. Antimicrobial Agents and Chemotherapy ... 2019/2020 Annual Report. isolate highlighting the genetic aspects of the antimicrobial resistance genes. Widespread antimicrobial resistance encourages repurposing/refining of nonantimicrobial drugs for antimicrobial indications. Phone: (202) 737-3600, Copyright © 2021 American Society for Microbiology | Privacy Policy | Website feedback, Print ISSN: 0066-4804; Online ISSN: 1098-6596, Recombinant Paraprobiotics as a New Paradigm for Treating Gastrointestinal Nematode Parasites of Humans, Dihydrotanshinone I Is Effective against Drug-Resistant Helicobacter pylori In Vitro and In Vivo, Mechanisms of Action: Physiological Effects, Journal of Microbiology & Biology Education, Microbiology and Molecular Biology Reviews, Screening and Identification of Metacaspase Inhibitors: Evaluation of Inhibition Mechanism and Trypanocidal Activity, Gain-of-Function Mutations in Acid Stress Response (, Metabolites Potentiate Nitrofurans in Nongrowing, Effects of Regulatory Network Organization and Environment on PmrD Connector Activity and Polymyxin Resistance in, BKC-2, a New BKC Variant Detected in MCR-9.1-Producing, Replacement of S14 Protein in Ribosomes of Zinc-Starved Mycobacteria Reduces Spectinamide Sensitivity, Selection of Resistant Bacteria in Mallards Exposed to Subinhibitory Concentrations of Ciprofloxacin in Their Water Environment, Interplay among Different Fosfomycin Resistance Mechanisms in, Systematic Review of Mutations Associated with Isoniazid Resistance Points to Continuing Evolution and Subsequent Evasion of Molecular Detection, and Potential for Emergence of Multidrug Resistance in Clinical Strains of, Atypical Molecular Basis for Drug Resistance to Mitochondrial Function Inhibitors in, Susceptibility Trends of Zoliflodacin against Multidrug-Resistant, Most-Probable-Number-Based Minimum Duration of Killing Assay for Determining the Spectrum of Rifampicin Susceptibility in Clinical, Multiple Single-Nucleotide Polymorphism Detection for Antimalarial Pyrimethamine Resistance via Allele-Specific PCR Coupled with Gold Nanoparticle-Based Lateral Flow Biosensor, Alkoxylalkyl Esters of Nucleotide Analogs Inhibit Polyomavirus DNA Replication and Large T Antigen Activities, Efficacy of a Cap-Dependent Endonuclease Inhibitor and Neuraminidase Inhibitors against H7N9 Highly Pathogenic Avian Influenza Virus Causing Severe Viral Pneumonia in Cynomolgus Macaques, Absence of Lenacapavir (GS-6207) Phenotypic Resistance in HIV Gag Cleavage Site Mutants and in Isolates with Resistance to Existing Drug Classes, Potent Bispecific Neutralizing Antibody Targeting Glycoprotein B and the gH/gL/pUL128/130/131 Complex of Human Cytomegalovirus, Dissemination of Extended-Spectrum-β-Lactamase-Producing, Tetrahydrophthalazinone Inhibitor of Phosphodiesterase with, Activities of Quinoxaline, Nitroquinoxaline, and [1,2,4]Triazolo[4,3-a]quinoxaline Analogs of MMV007204 against, Deimmunized Lysostaphin Synergizes with Small-Molecule Chemotherapies and Resensitizes Methicillin-Resistant, Radicicol, a Novel Lead Compound against the Migratory-Stage Schistosomula of, Efficacy and Pharmacokinetics of Fosmanogepix (APX001) in the Treatment of, Dihydrotanshinone I Is Effective against Drug-Resistant, The Pharmacodynamic-Toxicodynamic Relationship of AUC and, A Second-Generation Fungerp Analog, SCY-247, Shows Potent, Efficacy of Rezafungin in Prophylactic Mouse Models of Invasive Candidiasis, Aspergillosis, and, An Integrated HOCl-Producing E-Scaffold Is Active against Monomicrobial and Polymicrobial Biofilms, A Matched Case-Case-Control Study of the Impact of Clinical Outcomes and Risk Factors of Patients with IMP-Type Carbapenemase-Producing Carbapenem-Resistant, Optimization of Fluconazole Dosing for the Prevention and Treatment of Invasive Candidiasis Based on the Pharmacokinetics of Fluconazole in Critically Ill Patients, Pharmacokinetic and Pharmacodynamic Profiling of Minocycline for Injection following a Single Infusion in Critically Ill Adults in a Phase IV Open-Label Multicenter Study (ACUMIN), Benznidazole in Cerebrospinal Fluid: a Case Series of Chagas Disease Meningoencephalitis in HIV-Positive Patients, Model-Optimized Fluconazole Dose Selection for Critically Ill Patients Improves Early Pharmacodynamic Target Attainment without the Need for Therapeutic Drug Monitoring, Completion and Adverse Drug Events of Latent Tuberculosis Infection Treatment in Patients Receiving Dialysis: Predictors and Impacts of Different Regimens in a Prospective Cohort Study, Population Pharmacokinetic Analysis and Dose Regimen Optimization in Japanese Infants with an Extremely Low Birth Weight, Piperaquine Pharmacokinetics during Intermittent Preventive Treatment for Malaria in Pregnancy, A Single- and Multiple-Dose Study To Characterize the Pharmacokinetics, Safety, and Tolerability of Imipenem and Relebactam in Healthy Chinese Participants, Population Pharmacokinetic and Pharmacokinetic/Pharmacodynamic Analyses of Cefiderocol, a Parenteral Siderophore Cephalosporin, in Patients with Pneumonia, Bloodstream Infection/Sepsis, or Complicated Urinary Tract Infection, Minocycline Alone and in Combination with Polymyxin B, Meropenem, and Sulbactam against Carbapenem-Susceptible and -Resistant, The Polyaminoisoprenyl Potentiator NV716 Revives Old Disused Antibiotics against Intracellular Forms of Infection by, Population Pharmacokinetics of Tenofovir in Pregnant and Postpartum Women Using Tenofovir Disoproxil Fumarate, on behalf of the IMPAACT P1026s Protocol Team, Population Pharmacokinetics of Intravenous Ganciclovir and Oral Valganciclovir in a Pediatric Population To Optimize Dosing Regimens, Predicting the Disposition of the Antimalarial Drug Artesunate and Its Active Metabolite Dihydroartemisinin Using Physiologically Based Pharmacokinetic Modeling, Favipiravir and the Need for Early Ambulatory Treatment of COVID-19, Evidence-Based Guidelines Should Be Used To Inform COVID-19 Management, Correction for Arias et al., “Chitosan Ameliorates, New Perspectives on Antimicrobial Agents: Remdesivir Treatment for COVID-19, Mechanism-of-Action Classification of Antibiotics by Global Transcriptome Profiling, Fact versus Fiction: a Review of the Evidence behind Alcohol and Antibiotic Interactions, Nafamostat Mesylate Blocks Activation of SARS-CoV-2: New Treatment Option for COVID-19, Submission, Review, & Publication Processes. The reliance on one drug, praziquantel, to treat the parasitic disease schistosomiasis in millions of people a year shows the need to further develop a pipeline of new drugs to treat this disease. The Journal of Antimicrobial Chemotherapy is among the foremost international journals in antimicrobial research. Format-Neutral Submission* For initial submissions to ASM’s primary research journals, authors do not have to reformat their papers to meet ASM style requirements. Washington, DC 20036 Potent neutralizing monoclonal antibodies (MAbs) are promising drug candidates against HCMV infection. According to SCImago Journal Rank (SJR), this journal is ranked 2.096. It is a prodrug that once activated by nitroreductases goes on to inhibit bacterial DNA, RNA, cell wall, and protein synthesis. Schistosomiasis poses a serious threat to human health and remains a major tropical and parasitic disease in more than 70 countries. Metacaspases (MCAs) are cysteine proteases present in fungi, protozoa, and plants. International Journal of Antimicrobial Agents. Impact Factor: 4.621 ℹ Impact Factor: 2019: 4.621 The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years.